![]() ![]() 4Ĭomplete PV isolation (PVI) by single-shot or point-by-point catheter ablation approach is the cornerstone of catheter ablation in AF patients. 3 In contrast, AF induced by pacing protocol during typical AFL ablation is a strong predictor for AF. 2 Pulmonary vein (PV) firing during AF episodes makes an essential contribution to initiating typical AFL. 1 The presence of AFL is documented in 20.6% of AF patients. Conclusion: This study suggested that prophylactic CTI ablation was an ineffective and inefficient approach in AF without documented typical atrial flutter patients.ĪF and atrial flutter (AFL) commonly coexist, and reveal a strong clinical interrelationship. Additional prophylactic CTI ablation to pulmonary vein isolation significantly increased the radio frequency application time (standardised mean difference 0.52 95% CI p=0.03). Prophylactic CTI ablation was associated with a higher recurrent AF rate (33.8% versus 27.1% risk difference 0.07 95% CI p=0.02). The risk of atrial tachyarrhythmias following a successful catheter ablation procedure was greater in the pulmonary vein isolation + CTI ablation group than pulmonary vein isolation alone group (34.8% versus 28.2% risk difference 0.08 95% CI p=0.04). Results: A total of 1,476 patients from four studies were included. The pooled effects were presented as the risk difference and standardised mean difference for dichotomous and continuous outcomes, respectively. ![]() The overall effects estimation was conducted using random effects models. Methods: A systematic review and meta-analysis study was conducted. The present study aimed to evaluate the role of prophylactic CTI ablation in this population. Background: The advantage of prophylactic cavotricuspid isthmus (CTI) ablation for AF patients without documented atrial flutter is still unclear. ![]()
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